TABLE 1

Table 1.  Clinical characteristics of sporadic Creutzfeldt-Jakob disease

Based upon the NIH series of 232 experimentally transmitted cases.

PERCENTAGE OF PATIENTS WITH SYMPTOMS OR SIGNS

SYMPTOMS/SIGNS

AT ONSET

ON FIRST EXAM

DURING COURSE

MENTAL DETERIORATION

69

85

100

MEMORY LOSS

48

66

100

BEHAVIORAL ABNORMALITIES

29

40

57

HIGHER CORTICAL FUNCTIONS

16

26

73

CEREBELLAR

33

56

71

VISUAL/OCULOMOTOR

19

32

42

VERTIGO/DIZZINESS

13

15

19

HEADACHE

11

11

18

SENSORY

6

7

11

INVOLUNTARY MOVEMENTS

4

18

91

MYOCLONUS

1

9

78

OTHER (INCLUDING TREMOR)

3

12

36

PYRAMIDAL

2

15

62

EXTRA-PYRAMIDAL

0.5

9

56

LOWER MOTOR NEURON

0.5

3

12

PSEUDOBULBAR

0.5

1

7

SEIZURES

0

2

19